Download Advances in Cancer Research, Vol. 3 by Jeese P. Greenstein, Alexander Haddow (Eds.) PDF

By Jeese P. Greenstein, Alexander Haddow (Eds.)

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Because Dr. Koch persisted such huge persecution in regard to his technology, he decided that the medical/pharmacological may ceaselessly stay unwilling to independently display screen, record or validate any of his ongoing laboratory learn or scientific case histories; consequently considering his loss of life, December nine, 1967, there were no genuine Koch Reagents reproduced. It used to be end result of the scurrilous intentions held by way of the medical/pharmacological that Dr. Koch deliberately withheld particular wisdom required within the construction of doable Koch Reagents. (Therefore, any claims on the contrary may be considered as suspect. )

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They obtained tar from cigarettes smoked mechanically under conditions which approximated to the physical conditions of normal smoking and applied it three times a week to the skin of mice, until a carcinoma appeared or the animal died. To avoid toxic reactions from the nicotine content of the tar, the dose given initially was small and it was increased gradually over the following two months. The first papilloma appeared after eight months of painting: the first carcinoma, after one year. , 58 %) finally developed cancer.

Reproduced from a paper by Dr. E. C. ) From this point of view, it is difficult t o believe that the increase in mortality from lung cancer can have been directly due to pollution with chimney smoke or with petrol or oil fumes. On the one hand, the amount of coal consumed in the industrialized countries has not increased greatly, and the total amount of smoke pollution has probably decreased because of greater efficiency of combustion (in Britain, for example, coal consumption increased from about 165 million tons in 1900 to 206 million tons in 1953, but the amount burnt in gasworks and electricity-generating stations increased from 23 million tons in 1921* to 64 million tons in 1953.

Kennaway (1924, 1925) has shown that strong heating of acetylene and other unsaturated materials produces carcinogenic tars a t temperatures of 700°C. and above, and Fishel and Haskins (1949) showed that acetylene was present in tobacco smoke. The temperature of combustion in ordinary cigarettes, in paper “cigarettes,” in a pipe, and in a cigar, were, according to Lindsey (1954 and personal communication), as follows: Ordinary cigarette Paper “cigarette ” Pipe Cigar (Havana) Quiescent Combustion Temperature 650°C.

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